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Depression Anxiety and Pathophysiology Presentation

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DEPRESSION ANXIETY WHAT IS DEPRESSION? • It is normal for everyone to have their ups and downs. But depression is a serious condition where these feelings affect you feel, think, and handle daily activities, such as sleeping, eating, or working. • It is an illness that can affect anyone—regardless of age, race, income, culture, or education. Research suggests that genetic, biological, environmental, and psychological factors play a role in depression. • Depression may occur with other mental disorders and other illnesses, such as diabetes, cancer, heart disease, and chronic pain. Depression can make these conditions worse, and vice versa. Sometimes medications taken for these illnesses cause side effects that contribute to depression symptoms. (MedlinePlus, 2021 PATHOPHYSIOLOGY • • • • • • • One believed cause of depression is a serotonin imbalance. Serotonin is believed to help ward off feelings of fear, helplessness and depression. There has been a correlation between hypersecretion of cortisol and depression. About 5-10% of patients with depression have a thyroid disorder. A thyroid panel should be obtained on all depressed patients. Symptoms of depression all point to a dysregulation of the hypothalamus. Genetics is also another believed cause of depression. Psychosocial factors also contribute to depression. Stressful events seem to precede the first episodes of mood disorders and there is speculation that this leads to lasting changes i ...
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