Cause of The Periorbital Edema Discussion

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The differential diagnosis for the cause of the periorbital edema can become difficult. Specially

if the patient is over 65 years of age. Geriatric patients can have co-morbidities than can impact

the eye. The usual causes are trauma and infectious causes that can be bacterial or fungal and

generate orbital cellulitis. There are other differentials like sarcoidosis, Wegener’s disease.

Another consideration as a cuase is tumors like lymphoma, lymphangioma, lacrimal gland

tumors and cavernous hemangioma and angiosarcoma (Chow & Ang, 2021). There is also a

possibility of a carotid cavernous fistula, cavernous sinus thrombosis.

Considering that many geriatric patients take several medications the fact that the periorbital

edema be a consequence of the drug needs to be evaluated.

According to Yu & Guan, 2020). the most recent generation of bisphosphonates, “contain a

nitrogen group that has been reported to activate gamma delta (γδ) T-cells and lead to phase

reaction. It has been suggested that this mechanism in amino-bisphosphonates can cause ocular

inflammation, although rarely. In recent years, there have been multiple reports of inflammatory

ocular side effects from amino- bisphosphonates”.

Reference

Chow, K. Y., Ko, S., & Ang, Q. (2021). Rapidly Progressive Periorbital Oedema: A Case of

Cutaneous Angiosarcoma. Case reports in oncology, 14(1), 531–537.

https://doi.org/10.1159/000514304

Yu, J., & Guan, J. (2020). Bisphosphonate-Induced Acute Orbital Inflammation in a Patient With

Underlying Thyroid Ophthalmopathy. Cureus, 12(12), e12024.

https://doi.org/10.7759/cureus.12024

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The differential diagnosis for the cause of the periorbital edema can become difficult. Specially if the patient is over 65 years of age. Geriatric patients can have co-morbidities than can impact the eye. The usual causes are trauma and infectious causes that can be bacterial or fungal and generate ...
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Tags: periorbital edema Sarcoidosis geriatric patients Lacrimal Gland Tumors trauma and infectious

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NRS 493 Grand Canyon University Nursing Practice Literature Evaluation Table Analysis

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NRS 493 Grand Canyon University Nursing Practice Literature Evaluation Table Analysis

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NRS 493 Grand Canyon University Nursing Practice Literature Evaluation Table Analysis

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