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Heart Failure Is the Pathophysiological State Presentation

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Heart Failure Kareem L. O Definitions • Heart failure is the pathophysiological state in which an abnormality of cardiac function is responsible for failure of the heart to pump blood at a rate commensurate with the metabolic requirements of the body and/or the heart is able to do so only from an elevated filling pressure. (Eugene Braunwald 1980) • Heart Failure is defined by symptoms of heart failure, objective evidence of cardiac dysfunction and response to treatment targeted at heart failure (Task force o the ESC) Definitions • HF is a clinical syndrome caused by an abnormality of the heart and recognised by a characteristic pattern of haemodynamic, renal, neural and hormonal responses (Philip Poole-Wilson 1995) • A complex clinical syndrome resulting from any structural or functional cardiac disorder that impairs the ability of the ventricles to fill with or eject blood1 INTRODUCTION • … a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fi ll with or eject blood. ACC and AHA Task Force on Practice Guidelines. 2009 Focused Update Incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation 2009; 119: e391–e479 Epidemiloligy • 15 Million people are afflicted worldwide • Affects bpopulationetween 0.4 and 2% of the world’s, a prevalence similar to that of DM • Prev as high as 10% in the elderly • Pr ...
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