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Cleft Lip and Palate Presentation

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Dr. M. Akinlosotu OUTLINE  Introduction  Epidemiology  Aetiopathogenesis  Classification  Clinical features  Diagnosis  Treatment  Prevention INTRODUCTION  Cleft lip and palate also known as orofacial clefts. They are congenital defects in the formation of lip and palate resulting in partial or total splitting of the two sides of the lips and/or palate.  The orofacial clefts are related embryologically, functionally and genetically. However, each of them can exist alone or in combination or with other birth defects i.e as cleft lip, cleft lip and palate or as cleft palate. EPIDEMIOLOGY  The incidence ranges between 1:600 to 1: 2500 livebirth. Incidence of cleft lip with or without cleft palate is ≈1/750 white births; the incidence of cleft palate alone is ≈1/2,500 white births  The prevalence of clefts varies considerably in different racial groups. The lowest rate is for blacks. A high prevalence of Cleft Lip/Palate was found in the Japanese population, and the highest prevalence was found for the North American Indian populations  Cleft lip is more common in males while cleft palate is more common in females. However, cleft lip and palate is more common in males.  The incidence of associated congenital malformations (chromosomal aneuploidy, holoprosencephaly) and of impairment in development is increased in children with cleft defects, especially in those with cleft palate alone. Aetiology  Exact causes are un ...
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