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Sindromes mielodisplasicos

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Tecnologico de Monterrey
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Hematología Falla medular SÍNDROMES MIELODISPLÁSICOS Generalidades • • • • • SMD: neoplasia mieloide caracterizada por: o Proliferación clonal de células madre hematopoyéticas o Anormalidades genéticas recurrentes o Mielodisplasia o Hematopoyesis inefectiva o Citopenia en sangre periférica o Alto riesgo de evolución a LMA OMS: citopenia persistente en una o más líneas celulares (sangre periférica) y displasia morfológica ≥10% en más líneas celulares (médula ósea). o Puede ser primaria o secundaria (por QT/RT) Más común en adultos mayores o Edad media de presentación: 70 años o Rara vez ...
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