R is a free statistical software that is frequently and widely used. Go to R-Project for Statistical Computing (Links to an external site.)Links to an external site. to download the R software to your computer (follow the instructions provided in the attached R Installation Instructions sheet). The R Project website (Links to an external site.)Links to an external site. provides a brief introduction to R that you may also want to review. Like SAS, R is code-driven software that provides computation and graphics easily. This means that you need to write code in order to obtain the results. In this CT assignment, you will write code to find the probabilities. Some R example code to find the probabilities under specific distributions are given in Section 1.11 of zyBooks. For each problem, write an R code to compute each probability.(a) Binomial Distribution: X ~ Bin(10, 0.7) (i) P(X = 2) (ii) P(X < 2) (iii) P(X > 2) (iv) P(1 < X < 7)(b) Normal Distribution: X ~ N(0, 4). Note that variance is 4 and, hence, the standard deviation is 2. (i) P(X < 3) (ii) P(X > 3) (iii) P(1 < X < 3)(c) Choose either (a) or (b) and interpret the results in a real-life scenario. Make sure to define X and interpret each probability. For parts (a) and (b), take screenshots of R codes and the answers. Copy and paste the screenshot(s) into a Word document and submit the Word file in Canvas.

Select a procurement document for the turnaround project and explain your selection; develop a proposal evaluation method for the turnaround project that will be used to select a supplier.This portfolio work, project procurement and evaluation, is based on your selected business or IT project. You may choose to base your assessment on the Revive LLC case study for the development of a new online employee orientation module, or you may select an organization of your own choosing. Both human resource (HR) and information technology (IT) employees, as well as contractors, will be utilized in this project.Project Procurement Management is defined "as a methodology that includes the processes necessary to purchase or acquire products, services, or results needed from outside the project team" (Project Management Institute,2017).The procurement process should be dynamic and flexible to ensure the best combination of quality and pricing is obtained. For a more complex process many factors should enter into the decision-making process to obtain the best possible outcome with the lowest total cost of ownership, or TCO.Per the PMBOK® Guide, and as referenced in Kerzner (2017), project procurement management includes the processes where the project obtains a product or service from outside the project organization. The organization's perspective regarding procurement can either be as the buyer or the seller of the product or service. Project procurement management also includes the contract management and change control processes that are required to administer the signed contracts or any issued purchase orders. Project procurement management includes the following four key or major processes (Project Management Institute, 2017, Chapter 12):1. Plan Procurements – the process of documenting purchasing decisions, specifying the approach, and identifying potential sellers.2. Conduct Procurements – the process of obtaining seller responses, selecting a seller, and awarding a contract.3. Control Procurements – the process of managing the procurement relationships, monitoring contract performance, and making changes and corrections as appropriate, and closing out contracts.

Bipolar disorder is a unique disorder that causes shifts in mood and energy, which results in depression and mania for patients. Proper diagnosis of this disorder is often a challenge for two reasons: 1) patients often present as depressive or manic but may have both; and 2) many symptoms of bipolar disorder are similar to other disorders. Misdiagnosis is common, making it essential for you to have a deep understanding of the disorder’s pathophysiology. For this Assignment, as you examine the patient case study in this week’s Learning Resources, consider how you might assess and treat patients presenting with bipolar disorder.  Marcus, an 18-year-old high school senior, presents with symptoms of difficulty sleeping and feeling sad, which result in an initial diagnosis of depression. His mother later reports, however, that Marcus exhibits symptoms of irritability and risk-taking behaviors. (His little brother reported to his mother that they were driving over 90 miles an hour on the highway.) After further evaluation, Marcus’ psychiatric nurse practitioner diagnoses him with bipolar disorder. Cases like this are not uncommon with bipolar disorder, as initial assessments rarely provide all the information needed. In your role, as a psychiatric nurse practitioner, you must develop strategies for properly assessing and diagnosing these patients because treatments for bipolar disorder are significantly different than treatments for depression or other mood disorders. Assignment: you will write a 5–6-page paper on the topic of bipolar and bipolar and related disorders. You will create this guide as an assignment; therefore, a title page, introduction, conclusion, and reference page are required. You must include a minimum of 3 scholarly supporting resources outside of your course provided resources. In your paper, you will choose one of the following diagnoses: Bipolar I, Bipolar II, Cyclothymic Disorder, Substance/Medication-Induced Bipolar and Related Disorder, Bipolar and Related Disorder Due to Another Medical Condition. Your paper will include discussion for your chosen diagnosis of bipolar and related disorder on the following: Prevalence and Neurobiology of your chosen disorder Discuss the differences between your chosen disorder and one other bipolar and related disorders in relation to the diagnostic criteria including presentation of symptoms according to DSM 5 TR criteria Discuss special populations and considerations (children, adolescents, pregnancy/post-partum, older adult, emergency care) for your chosen bipolar and related disorder; demonstrating critical thinking beyond basics of HIPPA and informed consent with discussion of at least one for EACH category:  legal considerations, ethical considerations, cultural considerations, social determinants of health Discuss FDA and/or clinical practice guidelines approved pharmacological treatment options in relation to acute and mixed episodes vs maintenance pharmacological treatment for your chosen bipolar and related disorder Of the medication treatment options for your chosen disorder discuss side effects, FDA approvals and warnings.  What is important to monitor in terms of labs, comorbid medical issues with why important for monitoring Provide 3 examples of how to write a proper prescription that you would provide to the patient or transmit to the pharmacy.  Note: Support your rationale with a minimum of five academic resources. While you may use the course text to support your rationale, it will not count toward the resource requirement. You should be utilizing the primary and secondary literature. To prepare for this Assignment: Review this week’s Learning Resources, including the Medication Resources indicated for this week.  Reflect on the psychopharmacologic treatments you might recommend for the assessment and treatment of patients requiring bipolar therapy. The Assignment: 5 page Prevalence and Neurobiology of your chosen disorder Discuss the differences between your chosen disorder and one other bipolar and related disorders in relation to the diagnostic criteria including presentation of symptoms according to DSM 5 TR criteria Discuss special populations and considerations (children, adolescents, pregnancy/post-partum, older adult, emergency care) for your chosen bipolar and related disorder; demonstrating critical thinking beyond basics of HIPPA and informed consent with discussion of at least one for EACH category:  legal considerations, ethical considerations, cultural considerations, social determinants of health Discuss FDA and/or clinical practice guidelines approved pharmacological treatment options in relation to acute and mixed episodes vs maintenance pharmacological treatment for your chosen bipolar and related disorder Of the medication treatment options for your chosen disorder discuss side effects, FDA approvals and warnings.  What is important to monitor in terms of labs, comorbid medical issues with why important for monitoring Provide 3 examples of how to write a proper prescription that you would provide to the patient or transmit to the pharmacy.  Note: Support your rationale with a minimum of five academic resources. While you may use the course text to support your rationale, it will not count toward the resource requirement. You should be utilizing the primary and secondary literature. Review the following medications: amitriptyline bupropion citalopram clomipramine desipramine desvenlafaxine doxepin duloxetine escitalopram fluoxetine fluvoxamineimipramine ketamine mirtazapine nortriptyline paroxetine selegiline sertraline trazodone venlafaxine vilazodone