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Case discussion atherosclerosis

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Arteriosclerotic Vascular Disease Group 8 CASE • LM is 45 yo female, has chronic history of Angina. She has Type II diabetes and known to be a heavy chain smoker. She also complains of intermittent claudication • Ecg :sinus, nonspecific for infarction • Trop I negative, CKMB non elevated • Chest xray: atherosclerotic aorta PERTINENT DATA • LM is 45 yo female, has chronic history of Angina. She has Type II diabetes and known to be a heavy chain smoker. She also complains of intermittent claudication • Ecg :sinus, nonspecific for infarction • Trop I negative, CKMB non elevated • Chest x-ray: atherosclerotic aorta Definition of Terms • Angina - chest pain or discomfort caused when the heart muscle does not get enough oxygen-rich blood • Intermittent Claudication - a crampy, tired, and sometimes burning pain in one or both legs that comes and goes due to poor circulation of blood in the arteries of the legs GUIDE QUESTIONS 1. What is the cause of this patient’s Angina and LE disease? 2. Discuss the basic biochemical explanation of this condition 3. Discuss how atherosclerosis form 4. Discuss how diabetes affects lipid Cause of Angina and Claudication ATHEROSCLEROSIS or BUILD UP OF LIPID-RICH PLAQUES BLOCKAGE OF BLOOD VESSELS PAIN IN THE CHEST AND LEGS POOR BLOOD CIRCULATION POOR BLOOD CIRCULATION Type II Diabetes Heavy chain smoking Affects viscosity of blood, making its flow slower than normal thus affecting transport of blood Nicotine ac ...
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