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Pathophysiology Paper

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Running head: CIRRHOSIS 1
Cirrhosis
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CIRRHOSIS 2
Cirrhosis
Cirrhosis is a liver disorder whereby the liver tissue is replaced with scar tissue resulting
in liver dysfunction. The scar tissue blocks blood flow in the liver leading to slow processing of
nutrients and drugs and other substances such as hormones. According to the Center for Disease
Control and Prevention, cirrhosis was the 12
th
leading cause of death by the year 2009 with men
recording a higher death percentage than women. As well, it is one of the most costly diseases
regarding treatment and maintenance. It is estimated that the diseases account for 27,000 deaths
in the United States each year. The prognosis of the disease depends on the cause of the disease
with alcohol cirrhosis having the worst (Tsochatzis, Bosch & Burroughs, 2014). As such, those
suffering from hepatitis cirrhosis have higher chances of survival.
Common Causes
The primary cause of liver cirrhosis is Alcohol Liver Disease, which develops in heavy
alcohol drinkers. The alcohol disrupts the normal breakdown of fats and proteins resulting in
accumulation of these products in the liver. Another cause of this disorder is steatohepatitis a
condition that leads to accumulation of fat in the liver tissue that turns into scar tissue over time.
As well, chronic hepatitis C and B can cause cirrhosis due to the presence of hepatitis C or B
virus in the body. The two viruses are known to cause inflammation and damage to the liver
tissues. Primary biliary cirrhosis is a type of cirrhosis, which results from damaged bile ducts
consequently leading to liver damage. Apart from that autoimmune hepatitis can cause
inflammation of the liver which in turn leads to liver dysfunction and hence cirrhosis
(Tsochatzis, Bosch & Burroughs, 2014). Other causes of cirrhosis include Wilson’s disease that

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Running head: CIRRHOSIS 1 Cirrhosis Name Institution CIRRHOSIS 2 Cirrhosis Cirrhosis is a liver disorder whereby the liver tissue is replaced with scar tissue resulting in liver dysfunction. The scar tissue blocks blood flow in the liver leading to slow processing of nutrients and drugs and other substances such as hormones. According to the Center for Disease Control and Prevention, cirrhosis was the 12th leading cause of death by the year 2009 with men recording a higher death percentage than women. As well, it is one of the most costly diseases regarding treatment and maintenance. It is estimated that the diseases account for 27,000 deaths in the United States each year. The prognosis of the disease depends on the cause of the disease with alcohol cirrhosis having the worst (Tsochatzis, Bosch & Burroughs, 2014). As such, those suffering from hepatitis cirrhosis have higher chances of survival. Common Causes The primary cause of liver cirrhosis is Alcohol Liver Disease, which develops in heavy alcohol drinkers. The alcohol disrupts the normal breakdown of fats and proteins resulting in accumulation of these products in the liver. Another cause of this disorder is steatohepatitis a condition that leads to accumulation of fat in the liver tissue that turns into scar tissue over time. As well, chronic hepatitis C and B can cause cirrhosis due to the presence of hepatitis C or B virus in the body. The two viruses are known to cause inflammation and damage to the liver tis ...
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