Study-of-glaucoma-in-eyes-with-shallow-anterior-chamber

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RAJIV GANDHI UNIVERSITY OF

HEALTH SCIENCES

IN KARNATAKA, BANGALORE

ANNEXURE – II

PROFORMA FOR REGISTRATION OF SUBJECTS

FOR DISSERTATION

1. Name of the candidate

and address

DR. SHRUTHI. S.SHENAVA

P.G. QUARTERS

YENEPOYA MEDICAL COLLEGE

HOSPITAL

DERALAKATTE

MANGALORE-575 018

2. Name of the Institution

YENEPOYA MEDICAL COLLEGE,

DERALAKATTE

MANGALORE-575 018

3. Course of Study and the

Subject

M.S.Degree in Ophthalmology

4. Date of admission to course

April, 2007

5. Title of the Topic

“Study of glaucoma in eyes with shallow

anterior chamber”

6. Brief Resume of the intended work:

6.1 Need for the study:

Glaucoma is a leading cause of irreversible blindness through out the world.

Angle closure glaucoma is a major cause of visual morbidity in East Asia.

The overall prevalence of primary angle-closures glaucoma

(PACG)) in a rural

population

of southern India was 1.58%. There was a female preponderance,

and the

disease tends to be asymptomatic

Eyes with primary angle closure tend to share certain biometric characteristics.

These include shallow anterior chamber depth (ACD), thick lens, anterior lens

position, small corneal diameter with small radius of curvature and a short axial

length

2,3

. Among these, the shallow anterior chamber depth is regarded as the

cardinal risk factor in most ethnic groups. Photogrammetric studies of all forms of

angle closure glaucoma have revealed anterior chamber depths, volumes and

diameters that are smaller than matched controls

. So one of the aims of this study

is to know the prevalence of angle closure glaucoma I n those patients who have a

shallow anterior chamber depth amongst those who attend the ophthalmology OPD

in Yenepoya Medical College.

Peripheral anterior synechiae compromise the drainage of the aqueous humor and

results in a rise of IOP, and thus contributes to the optic neuropathy. Hence it is

important to assess in detail those anterior chambers which on screening are found

to be suspiciously shallow, in order to detect the presence of peripheral anterior

synechiae. In this study, the association between the gonioscopic angle width and

peripheral anterior synechiae in the population with shallow anterior chamber will

also be studied.

It is well known that chronic angle closure and creeping angle closure are

relatively asymptomatic and may mimic Primary open angle glaucoma (POAG) in

their presentation. In chronic angle closure glaucoma the angle closure may be

either due to appositional or synechial mechanism. The more extensive the PAS, the

more chronic is the disease process in the patient of angle closure glaucoma.

Therefore the chronicity i.e. the extent of PAS is expected to correlate with the

severity of visual field defects. In this study I am going to analyze the field changes

in the patients with shallow anterior chamber and peripheral anterior synechiae or

appositional closure to determine the severity of visual loss and correlate it with

extent of the synechiae.

6.2 Review of Literature:

Glaucoma is a condition of multi- factorial optic neuropathy in which there is

characteristic acquired loss of optic nerve fibres. The definitive characteristics are

based on either visual field loss or appearance of the disc or retinal nerve fiber layer

defect associated either with a raised or normal IOP

Glaucoma is classified

on the basis of initiating events into

(A) Open angle glaucoma

(B) Angle closure glaucoma

(D) Glaucoma associated with systemic and other ocular disorders

It is estimated that by the year 2020, 79.6 million people would be burdened

by glaucoma. 47% of the glaucoma world wide would be in Asians with more than

75% being angle closure

. At present twelve million Indians are affected by

glaucoma accounting for 12.8% of the blindness in the country

Hospital based data from India report primary open angle glaucoma

(POAG) to be as common as primary angle closure glaucoma (PACG) with 45% to

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RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES IN KARNATAKA, BANGALORE ANNEXURE - II PROFORMA FOR REGISTRATION OF SUBJECTS FOR DISSERTATION 1. Name of the candidate and address DR. SHRUTHI. S.SHENAVA P.G. QUARTERS YENEPOYA MEDICAL COLLEGE HOSPITAL DERALAKATTE MANGALORE-575 018 2. Name of the Institution YENEPOYA MEDICAL COLLEGE, DERALAKATTE MANGALORE-575 018 3. Course of Study and the Subject M.S.Degree in Ophthalmology 4. Date of admission to course 24th April, 2007 5. Title of the Topic "Study of glaucoma in eyes with shallow anterior chamber" 6. Brief Resume of the intended work: 6.1 Need for the study: Glaucoma is a leading cause of irreversible blindness through out the world. Angle closure glaucoma is a major cause of visual morbidity in East Asia. The overall prevalence of primary angle-closures glaucoma (PACG)) in a rural population of southern India was 1.58%. There was a female preponderance, and the disease tends to be asymptomatic 1. Eyes with primary angle closure tend to share certain biometric characteristics. These include shallow anterior chamber depth (ACD), thick lens, anterior lens position, small corneal diameter with small radius of curvature and a short axial length 2,3. Among these, the shallow anterior chamber depth is regarded as the cardinal risk factor in most ethnic groups. Photogrammetric studies of all forms of angle closure glaucoma have revealed anterior chamber depths, volumes and diameters that are smaller than matched controls ...
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