drug study nursing

Content type

User Generated

Type

Study Guide

Uploaded By

Nffvtazragrkcreg96

Pages

Rating

Classifications

Mechanism of Action

Indication

Contraindication

Side Effects

Nursing Considerations

Generic Name:

amikacin sulfate

Brand Name:

Amikin

Anti-infective;

Aminoglycoside

 Semisynthetic

derivative of

kanamycin with

broad range of

antimicrobial

activity that

includes many

strains resistant

to other

aminoglycosides.

 Pharmacologic

properties are

essentially the

same as those of

gentamicin.

 Appears to

inhibit protein

synthesis in

bacterial cell and

is usually

bactericidal.

 Primarily for

short-term

treatment of

serious

infections of

respiratory

tract, bones,

joints, skin, and

soft tissue, CNS

(including

meningitis),

peritonitis

burns,

recurrent

urinary tract

infections

(UTIs).

 Unlabeled

Uses: Intrathec

al or

intraventricular

administration,

in conjunction

with IM or IV

dosage.

 History of

hypersensitivity

or toxic

reaction with

aminoglycoside

antibiotic.

 Safety during

pregnancy

(category C),

lactation,

neonates and

infants, or use

period

exceeding 14

years old is not

established.

Adverse Effects (1%)

 CNS:

Neurotoxicity:

drowsiness,

unsteady gait,

weakness,

clumsiness,

paresthesias,

tremors,

convulsions,

peripheral

neuritis.

 Special Senses:

Auditory–

ototoxicity, high-

frequency

hearing loss,

complete

hearing loss

(occasionally

permanent);

tinnitus; ringing

or buzzing in

ears;

 Vestibular:

dizziness, ataxia.

 GI: Nausea,

vomiting,

hepatotoxicity.

 Metabolic:

Hypokalemia,

hypomagnesemi

 Skin: Skin rash,

urticaria,

pruritus,

redness.

 Urogenital:

Oliguria, urinary

frequency,

hematuria,

Assessment & Drug Effects

 Baseline tests: Before initial

dose, C&S; renal function and

vestibulocochlear nerve

function

 Monitor peak and trough

amikacin blood levels: Draw

blood 1 h after IM or

immediately after completion

of IV infusion; draw trough

levels immediately before the

next IM or IV dose.

 Lab tests: Periodic serum

creatinine and BUN, complete

urinalysis. With treatment

over 10 d, daily tests of renal

function, weekly audiograms,

and vestibular tests are

strongly advised.

 Monitor serum creatinine or

creatinine clearance levels are

associated with toxicity.

 Monitor S&S of ototoxicity

(primarily involves the

cochlear (auditory) branch;

high-frequency deafness

usually appears first and can

be detected only by

audiometer); indicators of

declining renal function;

respiratory tract infections and

other symptoms indicative of

superinfections and notify

physician should they occur.

 Monitor for and report

auditory symptoms (tinnitus,

roaring noises, sensation of

fullness in ears, hearing loss)

and vestibular disturbances

(dizziness or vertigo,

nystagmus, ataxia).

tubular necrosis,

azotemia.

 Other:

Superinfections.

 Monitor & report any changes

in I&O, oliguria, hematuria, or

cloudy urine. Keeping patient

well hydrated reduces risk of

nephrotoxicity; consult

physician regarding optimum

fluid intake.

Patient & Family Education

 Report immediately any

changes in hearing or

unexplained ringing/roaring

noises or dizziness, and

problems with balance or

coordination.

 Do not breast feed while

taking this drug without

consulting physician.

Generic Name:

citicoline sodium

Brand Name:

Zynapse,

Somazina,

Cholinerv

CNS Stimulant,

Peripheral

Vasodilators,

Cerebral

Activators,

Nootropics

 Citicoline

increases blood

flow and O2

consumption in

the brain. It is

also involved in

the biosynthesis

action.

 Citicoline is

indicated in

CVD in acute

recovery phase

in severe s/sx

cerebrovascular

insufficiency

and in-cranial

traumatism and

their sequellae.

 Citicoline in

CVA, stimulates

brain function.

 Any allergy or

hypersensitivity

to the drug

 Hypertonia of

the

parasympatheti

c nervous

system

 Use cautiously

for pregnancy

and lactation

 Conscious use

for patient with

renal and

hepatic damage

 Fleeting and

discrete

hypotension

effect, increased

parasympathetic

effects, low

blood pressure

 Itching or hives,

swelling in face

or hands, chest

tightness,

tingling in

mouth and

throat

 Take Citicoline as prescribed

 Take Citicoline on time

 Monitor patients neurologic

status

 Note if there are signs of

slurring of speech

 Note for adverse reactions

 Titer medication when

discontinuing

 Teach patient on how to take

the drug

 Arrange for regular follow-ups

Generic Name:

diazepam

Brand Name:

Valium

Benzodiazepine,

Anxiolytic,

Antiepileptic,

Skeletal muscle

 Exact

mechanisms of

action not

understood;

 Management of

anxiety

disorders or for

short-term

relief of

 Contraindicated

with hypersensi

tivity to

benzodiazepine

s; psychoses,

 CNS: Transient,

mild drowsiness

initially;

sedation,

depression,

Assessment

 History: Hypersensitivity

to benzodiazepines;

End of Preview - Want to read all 24 pages?

Access Now

Unformatted Attachment Preview

Classifications Mechanism of Action Indication Contraindication Side Effects Nursing Considerations Generic Name: amikacin sulfate Brand Name: Amikin Anti-infective; Aminoglycoside Semisynthetic derivative of kanamycin with broad range of antimicrobial activity that includes many strains resistant to other aminoglycosides. Pharmacologic properties are essentially the same as those of gentamicin. Appears to inhibit protein synthesis in bacterial cell and is usually bactericidal. Primarily for short-term treatment of serious infections of respiratory tract, bones, joints, skin, and soft tissue, CNS (including meningitis), peritonitis burns, recurrent urinary tract infections (UTIs). Unlabeled Uses: Intrathecal or intraventricular administration, in conjunction with IM or IV dosage. History of hypersensitivity or toxic reaction with an aminoglycoside antibiotic. Safety during pregnancy (category C), lactation, neonates and infants, or use period exceeding 14 years old is not established. Adverse Effects (1%) CNS: Neurotoxicity: drowsiness, unsteady gait, weakness, clumsiness, paresthesias, tremors, convulsions, peripheral neuritis. Special Senses: Auditory–ototoxicity, high-frequency hearing loss, complete hearing loss (occasionally permanent); tinnitus; ringing or buzzing in ears; Vestibular: dizziness, ataxia. GI: Nausea, vomiting, hepatotoxicity. Metabolic: Hypokalemia, hypomagnesemia. Skin: Skin rash, urticaria, pruritus, redness. Urogenital: Oliguria, urinary fre ...
Purchase document to see full attachment