Describe the dominant oncogene expressed in the virus

timer Asked: Apr 17th, 2014

Question description

Rous Sarcoma Virus (RSV) is called an "acutely transforming retrovirus" since the viral genome contains a cellular oncogene called Src. Besides RSV, over 40 naturally occurring acutely transforming retroviruses have been isolated in nature that also carry cellular oncogenes. Five of these viruses are listed below. For each virus, (i) describe the dominant oncogene expressed in the virus, and (ii) briefly outline the mechanisms by which these oncogenes transform cells. 

1. Abelson murine leukemia virus

2. Fujinami sarcoma virus

3. Avian sarcoma virus CT10

4. Harvey murine sarcoma virus

5. Moloney murine leukemia virus

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