Attached are the details for both assignments. Make sure to answer in the same document........................................

In Module 3, Lecture 1, we learned about the four core principles of human subjects research (autonomy, beneficence, nonmaleficence, and justice) .For this assignment, consider what you read in Perusall activity by Johnston and Baylis (2004). Johnston and Baylis describe an older case of genome editing therapy for a disease called X-linked SCID (Severe Combined Immune Deficiency). Following a novel gene therapy for their X-linked SCID, two children in the clinical trial developed leukaemia. This article provides a case study of risks associated with genome editing for biomedical therapies. Johnston and Baylis article: "Gene Therapy:Two Steps Forward, one Step back" In at least 250 words (total): (1) Identify one of the four core principles of human subjects research at stake with this case. Explain why you think that the core principle you have chosen applies to this case. (2) Using the case describe in the Johnston and Baylis article, do the following: (a) Identify an ethical problem in the case. Explain why you believe that this is an ethical problem. (b) Identify ONE interested individual or institution (stakeholder) in this case. Explain why you believe that this individual or institution is a stakeholder in this case. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419760/

Part 1 Draft a letter in response to the complaint. Your letter should summarize why you believe the complaint is invalid and no on-site inspection is required. Keep in mind, simply stating that the complaint is invalid is not adequate. You must support your opinions in the letter. Part 2 Where does this type of complaint fit on OSHA’s priority criteria? What factors could have made this complaint non-formal rather than formal? What steps could you take as the employer to identify the employee who filed the complaint? What factors could result in this complaint being reclassified as a formal complaint? Part 3 1) Under what conditions can an employee be denied access to the opening conference, walk-around, and closing conference?   Your response should be at least 75 words in length. 2) Can an employee request that an attorney or union representative attend a private conference with the compliance officer? If the union demands to have a representative present, does the employee have to comply?   Your response should be at least 75 words in length.  3) If OSHA determines that an employer's response to a non-formal complaint is adequate, what options does the employee filing the non-formal complaint have?  Your response should be at least 75 words in length. 4) If the OSHA compliance officer requests documents that are not related to a formal complaint, what options do you believe the employer has?