carcinogenics that occurred after his exposure to radiation, health and medicine homework help

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Health Medical

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  • Patient worked for 10 years at a uranium mine, excavating uranium for a nearby nuclear power plant. Now, 25 years later, he has small cell lung cancer. Patient is anorexic and has lost a considerable amount of weight. His muscles are wasting, and he is weak. He tries to move around the house throughout the day but tires easily. It has been difficult for him to access care, and the treatment for his cancer is just starting.
  • With the ongoing exposure to the ionizing radiation, DNA damage occurred. Outline the three stages of carcinogenesis that occurred after his exposure to radiation.
  • a male is normally a fit and active, and his wife often commented on how much food he used to eat after a day at mine. Why would there be muscle wasting and weight loss now? Explain your answer using your
  • knowledge of the metabolic changes seen with cancer.

In some cancer patients,

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Explanation & Answer

Attached.

Stages of Cancer-Outline
I.
II.

Introduction
Stages
A. Initiation
B. Promotion
C. Progression

III.

Metabolic changes

IV.

Conclusion


Running head: STAGES OF CANCER

1

Stages of Cancer
Name
Institution

STAGES OF CANCER

2
Stages of Cancer
Introduction

Cancer is a genetic disorder that develops in three distinctive stages. Being a genetic
disease, changes that happen in the three stages of development are at the molecular level, and
they affect the structure of the genes. Therefore, gene expression is changed and cells begin
proliferating in an uncontrolled manner. The changes in gene expression that influence
proliferation of the cell in carcinogenesis start in the initiation stage of the neoplastic
development and continues in the progression and subsequently in the promotion faces. The
changes in cell growth in first two stages include apoptosis and proliferation happening at
different speeds but in a balanced manner (Prehn & Prehn, 2013). In the progression, the
balance is distorted and the rate of malignancy increases. Promotion is the intermediate step, and
it involves pre-neoplastic cell being beginning the process and therefore changing the existing
balance between apoptosis and progression.
Stages
Initiation
In the particular case, initiation of carcinogenesis was via exposure to radiation from the
radioactive Uranium. Therefore, the radiation causes changes that cannot be reversed in the
genetic material. The shifts in the DNA, therefore, cause the cells to become malignant and gain
immortality. In essence, the initiated cells in the stage are no...


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Really great stuff, couldn't ask for more.

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