Elaborate on Critical Review

User Generated

Trahvf05

Humanities

PSY 630

Description

Elaborate on the Topic for Your Critical Review

This assignment will be a continuation of the written assignment from Week One. Research a minimum of three peer-reviewed articles in addition to information from your text on the disorder you chose in Week One. Consider the key classes of drugs used to treat the disorder you chose in Week One and explain their action at the neurotransmitter system involved in the disease process. Analyze and describe the agonist-antagonist activity of the drugs and the receptor types and subtypes involved in the disorder. Elaborate on the receptor agonist-antagonist actions of the drugs and describe the most common side effects seen with these drugs. Evaluate the risk-benefits of drug use for this disorder.

The paper:

  • Must be three to five double-spaced pages in length, excluding title page and references page, and it must be formatted according to APA style as outlined in the Ashford Writing Center. (Links to an external site.)Links to an external site.
  • Must include a title page with the following:
    • Title of paper
    • Your name
    • Course name and number
    • Your instructor’s name
    • Date submitted
  • Must address the topic of the paper with critical thought.
  • Must use at least three peer-reviewed sources in addition to the text.
  • Must document all sources in APA style as outlined in the Ashford Writing Center.
  • Must include a separate references page that is formatted according to APA style as outlined in the Ashford Writing Center.

Carefully review the Grading Rubric (Links to an external site.)Links to an external site. for the criteria that will be used to evaluate your assignment.

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Explanation & Answer

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Running head: ALZHEIMER DISEASE

Alzheimer Disease
Name
Instructor
Course Title
Date

ALZHEIMER DISEASE

1
Alzheimer Disease

Degeneration of various structures in the brain is the primary characteristic of Alzheimer
disease which is caused by the growth of amyloid plaques and neurofibrillary tangles. As a
result, there may be a deficit of acetylcholine and other neurotransmitters. The primary
pharmacologic treatment of the disease is concerned with the correction of histopathology, as
well as the disorder and effects of biochemicals. The two cholinesterase inhibitors are the only
drugs that can combat cognitive symptoms of patients with Alzheimer disease because they can
break down acetylcholine in the synapse. Both drugs improve cognitive function modestly
(Grundman et al., 2004). However, discontinuation of these drugs makes them lose all benefits
because the disease advances to a level experienced in placebo-treated patients. They also have
side effects such as nausea and vomiting (Paterson &Nordberg, 2000). Other drugs that may be
used in the treatment of Alzheimer disease are estrogen, vitamin E, and selegiline.
Neurotransmitters enhancers such as nicotine are also being used to treat this disease.
Consider the critical classes of drugs used to treat the Alzheimer disease and explain
their action at the neur...


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