Description
Answer this question: How do antibiotics work? Antibiotics work through the concept of selective toxicity. For your response, research the concept of selective toxicity, and use your knowledge of bacterial and eukaryal cell structure, gained from the text readings and Exploration page, to answer the question. Make sure you write down the sources you use for your research. Start your discussion post with a definition of selective toxicity in your own words and a paragraph outlining possible antibiotic targets of bacterial cells. Your next paragraph will focus on penicillin. You should find one to two reliable sources that discuss how penicillin works. Focus on the structure that penicillin targets, and discuss how this relates to selective toxicity. Finally, consider how you could use the scientific method to learn about how antibiotics work. What questions would you want to research? What is your hypothesis? All references must be cited using APA Style.
3 pages
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Running Head: ANTIBIOTICS
ANTIBIOTICS
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ANTIBIOTICS
ANTIBIOTICS
Selective toxicity is a situation whereby antibiotics kill the bacterial cells without
affecting the host cells. Antibiotics are also antimicrobial agents which originate from the
substances of microorganisms that inhibit other microorganisms. Antibiotics work through the
process of selective toxicity that is by destroying bacterial cells and does not affect the host cells.
First and foremost antibiotics, work by initiating a Lytic cell death. To begin with, the bacteria
cell is enclosed in Peptidoglycan layers, which is a covalent cross-linked polymer. This layer of
the cell is crucial for the survival of the bacteria in unconducive environmental conditions.
Peptidoglycan maintenance is achieved by transglycosylase and transpeptidase enzymes
activities. These enzymes add disaccharide pentapeptides to enlarge the glycan threads of
surviving PG molecules and cross-link bordering peptide strands of undeveloped PG units,
respectively56. Therefore in this case antibiotics work by preventing the cross-linking of the
Peptidoglycan units. ...
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