Medicine powerpoint

Jun 30th, 2015
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Comprehensive power points in gynecology, internal medicine, ophthalmology, pharmacology, etc

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PHYSICAL TREATMENT INPSYCHIATRYElectro convulsive therapy(ECT)An effective treatment for patient with majordepressive illness and other serious mentalillnessPhysical rx con History-1934 Von Medura a psychitrist used seizurestreatment based on two observations(a)schizophrenic symptoms decreased after aseizure(b)schizophrenia and epilepsy it was incorrentlybelieved cannot coexist inthe same patientinduction of seizure would cure schizopreniaIn April 1938 the 1st Ect ,refered to aselectroshock was done in Rome by Lucio BiniMECHANISM OF ACTION Mechanism of action unknown but there several theories(a)Neurophysiological theory-during the seizure there is increase inblood flow ,use of glucose and oxygen in the brain and alsopermeability of blood brain barrier.After the seizure there is decrease inglucose,oxygen and permeability and this decrease is associated with atherapeutic effect.(bNeurochemical theory-after several session of ECT there isdown regulation of neurotrasmitter recepters(post synaptic betaadrenergic receptor(c)It affect the coupling of G protein to receptor,affect activity ofadenylyl cycliase and phospholipase C and the regulation of calciumentry into neuronsINDICATIONS 3 MAJOR CONDITIONS(A)Major depressive disorder(B) Manc episode(C) SchizophreniaINDICATION CONT Major depression-failed medication trial-have not tolerated medications-have severe psychotic symptoms-acutely suicidal or homicidalManic episode-qu

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