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Available online at www.sciencedirect.comDiagnostic Microbiology and Infectious Disease 63 (2009) 233 236www.elsevier.com/locate/diagmicrobioA global evaluation of voriconazole activity tested against recent clinicalisolates of Candida spp.Daniel J. Diekemaa,b,, Shawn A. Messerb , Richard J. Hollisb , Linda Boykenb ,Shailesh Tendolkarb , Jennifer Kroegerb , Ronald N. Jonesd , Michael A. Pfallerb,caDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USAbDepartment of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USAcDepartment of Epidemiology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USAdJones Microbiology Institute, North Liberty, IA 52317, USAReceived 17 August 2008; accepted 3 November 2008AbstractVoriconazole susceptibility testing was performed on 7191 Candida spp. from 78 centers worldwide between 2004 and 2007.Voriconazole was very active in vitro (MIC50/MIC90, 0.008/0.25 g/mL; 98% susceptible). In comparison to 5866 Candida spp. isolatescollected during global surveillance from 1997 to 2001, there were no changes in voriconazole mean MI

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