African trypanosomiasis

Apr 8th, 2015
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Study guide on African Trypanosomiasis

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AFRICAN TRYPANOSOMIASISEPIDEMIOLOGYSleeping sickness is re-emerging in Africaafter near elimination in early 1960.It is a major health problem in subsaharan Africa.55 million in 36 African countries areconsidered to be risk of disease.45,000 cases of African Trypanosomiasisreported to [W.H.O] 1999.W.H.O. believes the real number 300,000and 500,000DISTRIBUTIONEPIDIMIOLOGY..Angola, the Democratic Republic of Congo andSouthern Sudan the prevalence of the diseaseis 20% to 50% [T.b gambiense]East and Central Africa, including Uganda,Kenya, Tanzania, Ethiopia, Malawi, Zimbabweand Botswana [T.b rhodesiense]In U.S.A. 21 cases of East AfricanTrypanosomiasis since 1967IMPACT OF THE DISEASEThe disease has both socio-economic andcultural impacts- individuals- families- communitiesIt disrupts normal family lifeIt reduces household labourIt causes abortion and sterilityIt reduces productivity of patients and causesloss of income.THREE SPECIESEAST AFRICAN TRYPANOSOMIASIS-Trypanosoma brucei rhodesiense(Human)-Epidemics are rare.WEST AFRICAN TRYPANOSOMIASIS-Trypanosoma brucei gambiense(Human)-Epidemics are common.DISEASE IN ANIMALS (CATTLE)NAGANA-Trypanosoma brucei bruceiTRANSMISSIONBy bite of infected tsetse fly (GLOSSINA)Glossina is only found in Africa.Three important species of Glossina are: Glossina fusca (Forest species) Glossina morsitans (Thor

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