Rabies infection and management

Apr 8th, 2015
Studypool Tutor
Price: $20 USD

Tutor description

Study guide on Rabies infection and management

Word Count: 1000
Showing Page: 1/30
RABIESEU MBCHB 3DR D M KILLINGOINTRODUCTION An invariably lethal acute viral disease ofthe CNS that affects all mammals Caused by a bullet shaped single strandRNA virus Rhabdoviridae family, lyssagenus. There are at least 7 rabies relatedviruses in the genusEPIDEMIOLOGY In all regions of the world except antarctica,new zealand, japan, taiwan, sweden,norway, spain, hawaii Common in s.e. asia, the phillipines, africa,indian sub continent and tropical s. americaEPIDEMIOLOGY contd2 forms: urban rabies. Spread by unimmuniseddomestic dogs, cats Sylvatic rabies spread by wild game likeskunks, foxes, racoons, mongooses, wolvesand bats. Major source in the USTHE PATHOGEN Rhabdoviridae family, genus lyssa virus Bullet shaped virion containing a singlestranded rna genome that encodes 5structural proteins: 1. Outer glycoprotein primary target ofneutralising antibody 2. Nucleoprotein enables identification ofrabies virus variantsTHE PATHOGEN 3. Large polymerase protein 4. Phosphorylated protein 5. Matrix protein Each virion surrounded by a lipoproteinenvelop studded with glycoprotein spikeswhich attach to specific sites such asnicotinic Ach recs on plasma membranes ofmuscle cellsImmunohistochemical Staining (Red) of Rabies Virus Antigens inPeripheral Nerves of the Liver (Panels A and B), Kidney (Panel C),andArterial-Graft Transplants (Panel D).PATHOGENESIS I

Review from student

Studypool Student
" awesome work thanks "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1831 tutors are online

Brown University

1271 Tutors

California Institute of Technology

2131 Tutors

Carnegie Mellon University

982 Tutors

Columbia University

1256 Tutors

Dartmouth University

2113 Tutors

Emory University

2279 Tutors

Harvard University

599 Tutors

Massachusetts Institute of Technology

2319 Tutors

New York University

1645 Tutors

Notre Dam University

1911 Tutors

Oklahoma University

2122 Tutors

Pennsylvania State University

932 Tutors

Princeton University

1211 Tutors

Stanford University

983 Tutors

University of California

1282 Tutors

Oxford University

123 Tutors

Yale University

2325 Tutors