bleeding and hemostasis

Apr 15th, 2015
Studypool Tutor
Price: $20 USD

Tutor description

Study guide

Word Count: 533
Showing Page: 1/24
SURGICAL BLEEDING& HEMOSTASISDr MungatanaMarch 2013HemostasisObjective of hemostasis: Toprevent or terminate blood loss from a site ofvascular disruptionMechanism Formationof a stable clotThe Hemostatic EventsTransient VasospasmPlatelet PlugFibrin DepositionFibrinolysisHemostasis:BV InjuryTissueFactorNeuralBlood VesselPlateletCoagulationVasospasmActivationActivationPrimary hemostaticplugReducedPlt-FusionBloodflowThrombin,FibrinStable Hemostatic PlugTransient VasospasmThe initial response to vascular injuryMay be enough by itself to stop bleedingStimuli for vasoconstrictionStimuli for vasodilationTXA2 mostly from platelet AA5-HTBradykinin and fibrinopeptidesProstacyclin (PGI2)Factors affecting effectiveness of vasospasmTangent of injuryPerivascular pressureLinear bleeds more than cross sectionalSteroids, weight loss, ageingVascular abnormalitiesEhlers DanlosThe Role of PlateletsAre 200,000-400,000 with a lifespan 9 daysMediates primary hemostasis: reversible clot formed immediatelyafter injury . vW factor dependentUpon exposure to subendothelial collagen platelets undergo arelease reaction that recruits more platelets hence the primaryhemostasisFrom platelet AATXA mediates vasoconstriction and platelet aggregationProstacyclin (PGI2) the reve

Review from student

Studypool Student
" Excellent work as always thanks so much "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1829 tutors are online

Brown University

1271 Tutors

California Institute of Technology

2131 Tutors

Carnegie Mellon University

982 Tutors

Columbia University

1256 Tutors

Dartmouth University

2113 Tutors

Emory University

2279 Tutors

Harvard University

599 Tutors

Massachusetts Institute of Technology

2319 Tutors

New York University

1645 Tutors

Notre Dam University

1911 Tutors

Oklahoma University

2122 Tutors

Pennsylvania State University

932 Tutors

Princeton University

1211 Tutors

Stanford University

983 Tutors

University of California

1282 Tutors

Oxford University

123 Tutors

Yale University

2325 Tutors