Pharmacology notes

Apr 15th, 2015
Studypool Tutor
Price: $5 USD

Tutor description

Word Count: 739
Showing Page: 1/4
Tuesday, November 01, 2011METRIFONATEMetrifonate is an organophosphorous component used as an insecticide and then as an anthemintic for S. hematobiumMetrifonate is a prodrug that is converted nonenzymatically to dichlorvos (2,2 dichlorovinyl dimethyl phosphate DDVP) a potent cholinesterase inhibitor.OXAMNIQUINEThis is a second line drug to praziquantel for the tx of schistosomiasisMost strains of S. mansoni are highly susceptible to oxamniquine but S. hematobium and S. japonicum are virtually unaffected by the therapeutic doseBecause of low incidence of mild side effect together with the normally high efficacy after a single dose, oxamnoquine continues to be used in S. Mansoni control programs in S. AmericaPIPERAZINEA number of substituted piperazine derivatives have anhelmintic activity but none apart from the diethylcarbamazine has found a place in human therapeuticsPiperazine is highly effective against A lumbricoides and E vermiculalris. The predominant effect of piperazine on ascaris is a temporary paralysis that results in expulsion of the worm by peristalsisPiperazine acts as a GABA-receptor agonist. By increasing the Cl- conductance of the ascaris muscle

Review from student

Studypool Student
" Excellent work as usual "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1827 tutors are online

Other Documents

04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015

Brown University





1271 Tutors

California Institute of Technology




2131 Tutors

Carnegie Mellon University




982 Tutors

Columbia University





1256 Tutors

Dartmouth University





2113 Tutors

Emory University





2279 Tutors

Harvard University





599 Tutors

Massachusetts Institute of Technology



2319 Tutors

New York University





1645 Tutors

Notre Dam University





1911 Tutors

Oklahoma University





2122 Tutors

Pennsylvania State University





932 Tutors

Princeton University





1211 Tutors

Stanford University





983 Tutors

University of California





1282 Tutors

Oxford University





123 Tutors

Yale University





2325 Tutors