Pharmacology notes

Apr 15th, 2015
Studypool Tutor
Price: $5 USD

Tutor description

Word Count: 5660
Showing Page: 1/77
THE OVARY, ORAL CONTRACEPTIVES, INHIBITORS & ANTAGONISTS,& OVULATION - INDUCING AGENTS The ovary has important gametogenic functions that are integrated with itshormonal activity. At puberty, the ovary begins a 30- to 40-year period of cyclic function called themenstrual cycle because of the regular episodes of bleeding that are its mostobvious manifestation. It then fails to respond to gonadotropins secreted by the anterior pituitary gland,and the cessation of cyclic bleeding that occurs is called the menopause.NormalMenstrual Cycle At the beginning of each cycle, a variable number of follicles (vesicular follicles),each containing an ovum, begin to enlarge in response to FSH. After 5 or 6 days, one follicle, called the dominant follicle, begins to developmore rapidly. The outer theca and inner granulosa cells of this follicle multiply and, under theinfluence of LH, synthesize and release estrogens at an increasing rate. The estrogens appear to inhibit FSH release and may lead to regression of thesmaller, less mature follicles. The mature dominant ovarian follicle consists of an ovum surrounded by a fluidfilled antrum lined by granulosa and theca cells. The estrogen secretion reaches a peak just before midcycle, and the granulosacells begin to secrete progesterone. These changes stimulate the brief surge in LH and FSH release that precedesand causes ovulation. When the follicle ruptures, the ovum is released in

Review from student

Studypool Student
" Thanks, good work "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1829 tutors are online

Other Documents

04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015
04/15/2015

Brown University





1271 Tutors

California Institute of Technology




2131 Tutors

Carnegie Mellon University




982 Tutors

Columbia University





1256 Tutors

Dartmouth University





2113 Tutors

Emory University





2279 Tutors

Harvard University





599 Tutors

Massachusetts Institute of Technology



2319 Tutors

New York University





1645 Tutors

Notre Dam University





1911 Tutors

Oklahoma University





2122 Tutors

Pennsylvania State University





932 Tutors

Princeton University





1211 Tutors

Stanford University





983 Tutors

University of California





1282 Tutors

Oxford University





123 Tutors

Yale University





2325 Tutors