Pharmacology notes

Apr 15th, 2015
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When your head is in the ovenand your bum is in the fridge,your average body temperaturemay be fine but you dont feel sogood!Beyond mountains there aremountains(Haitian Proverb)43HYPERTENSIONBYPROF. McLIGEYO.S.OU.S. Department ofHealth and HumanServicesNational Institutesof HealthNational Heart, Lung,and Blood InstituteThe Seventh Report of theJoint National Committee onPrevention, Detection,Evaluation, and Treatment ofHigh Blood Pressure (JNC 7)PurposeWhy JNC 7?Publication of many new studies.Need for a new, clear, and concise guideline useful forclinicians.Need to simplify the classification of BP.New Features and Key Messages For persons over age 50, SBP is a more important than DBP as CVD riskfactor. Starting at 115/75 mmHg, CVD risk doubles with each increment of20/10 mmHg throughout the BP range. Persons who are normotensive at age 55 have a 90% lifetime risk fordeveloping HTN. Those with SBP 120139 mmHg or DBP 8089 mmHg should beconsidered prehypertensive who require health-promoting lifestylemodifications to prevent CVD.New Features and Key Messages(Continued) Thiazide-type diuretics should be initial drug therapy for most, eitheralone or combined with other drug classes. Certain high-risk conditions are compelling indications for other drugclasses. Most patients will require two or more antihypertensive drugs toachieve goal BP. If BP is >20/10

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