Pharmacology notes

Apr 15th, 2015
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Pharmacology Semester 1 page 1 of 3By Duy Thai, 1997ADRENERGIC PHARMACOLOGY I When adrenaline is injected into a person we see 2 things happening: A rise in blood pressure (and maybe a small drop in blood pressure) A rise in heart rate Adrenaline causes these effects by acting on 2 different receptors - one on the peripheral blood vessels and one onthe heart. The peripheral receptor is the receptor and causes vessel constriction There is also a receptor which adrenaline can act on to cause a small degree of vessel dilation,but the effect predominates. The heart receptor is 1 and causes increased force and rate of contraction. When ergot alkaloids ( antagonists) are given in conjunction with adrenaline, we see a fall in blood pressure butthe heart rate remains increased. The ergot alkaloids inhibit the receptor Hence, adrenali

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