Pharmacology notes

Apr 16th, 2015
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Wednesday, August 03, 2011VIRAL DISEASES & viral chemotherapyVast number of viruses cause infectious diseasesStructural xsteristics Basic structural xsteristics such as genome type, virion shape and replication site, generally share the same features among virus species within the same familyANTIVIRAL DRUGSThese are a class of medication used specifically for treating viral infectionsLike Antibiotics, specific antivirals are used for specific virusesUnlike most antibiotics, antivirals don't destroy the target pathogen; instead they inhibit their developmentThey should be distinguished from viricides, which are not medication but destroy virus particles outside the bodyMost of the antivirals now available are designsed to help deal with HIV, herpes viruses, hepatitis B and B viruses which can cause liver cancer and influenza A and B virusesDesigning safe and effective antiviral drugs is difficult because the viruses use the host cell to replicateAntiviral drugsGeneral idea behind modern antiviral design is to identify viral proteins or parts of proteins that can be disabledVaccinesThese bolster the body's immune system to bettwe attack viruses in the "complete particle" stage, outside the organisms' cellThey traditionally consists of an attenuated (weakened or killed) version of the virusThe vaccines can in rare cases, harm the host by inadvertently infecting the host with a full blown viral occupancyVIRUS LIFE CYCLEViruses consists of a genome and som

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