Pathology notes

Apr 16th, 2015
Studypool Tutor
Price: $555 USD

Tutor description

Word Count: 546
Showing Page: 1/12
Peter Kinyanjui..HEMATOPOIETIC SITESEmbronic periodFrom 2nd wkYolk sac3rd month to first2wks after birthLiver and spleen4th & 5th monthcommencement in the BM,becomes fully activeby 7th & 8th monthsChildhood & adultlifeBM. The spleen and liver can also resume their foetalhaematopoietic role in certain pathologic conditionsand is called extramedullary haematopoiesis. In the bone marrow, developing blood cells aresituated outside the marrow sinuses, from where aftermaturation they enter the marrow sinuses, the marrowmicrocirculation and thence released into circulation.HEMATOPOIETIC STEM CELLSHaematopoieisis involves two stages:mitotic division or proliferation, anddifferentiation or maturationas CD34 and adhesion proteins which help the stemcells to home to the BM when infused. The stem cells have the appearance of small orintermediate-sized lymphocytes and their presence inthe marrow can be demonstrated by cell culturetechniques by the growth of CFU pertaining todifferent cell lines The bone marrow provides a suitable environment forgrowth and development of stem cells The stem cells have the capability of maintaining theirprogeny by self-replication. stem cells express a variety of cell surface proteins such. Myeloid haematopoiesis is regulated by endogenousglycoproteins called as growth factors, cytokines andhormonesErythropoietinGranulocyte colony-stimulating fact

Review from student

Studypool Student
" Thank you, Thank you, for top quality work, this is your guy!! "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1822 tutors are online

Other Documents

04/16/2015
04/16/2015
04/16/2015
04/16/2015
04/16/2015
04/16/2015
04/16/2015
04/16/2015
04/16/2015
04/16/2015

Brown University





1271 Tutors

California Institute of Technology




2131 Tutors

Carnegie Mellon University




982 Tutors

Columbia University





1256 Tutors

Dartmouth University





2113 Tutors

Emory University





2279 Tutors

Harvard University





599 Tutors

Massachusetts Institute of Technology



2319 Tutors

New York University





1645 Tutors

Notre Dam University





1911 Tutors

Oklahoma University





2122 Tutors

Pennsylvania State University





932 Tutors

Princeton University





1211 Tutors

Stanford University





983 Tutors

University of California





1282 Tutors

Oxford University





123 Tutors

Yale University





2325 Tutors