Pathology notes

Apr 16th, 2015
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INTERPRETATION OF PERIPHERALBLOOD SMEARSDorah WangaliaDefination When a peripheral blood sample is smearedon a slide and stained, it is known as aperipheral blood filmoften follows a complete blood count It allows for examination of the physicalcharacteristics of the red cells, white cells andplatelets under the microscope. Additionally,it helps detect parasites or abnormal cells inthe blood. Thus the peripheral blood film is animportant indicator of haematological andother disease.Information provided on theperipheral blood films The erythrocytes (red blood cells): a note will be made of their size,shape, any membrane changes, colour and stippling. Any inclusionbodies (eg, Howell-Jolly bodies or malarial parasites) will also benoted. Other abnormalities include red cell rouleaux, red cellnucleation and the presence of reticulocytes. The leukocytes (white blood cells): the number and morphology ofthese cells are noted, as well as abnormalities such as toxicgranulation or dysplastic changes. Presence of abnormal cells isimportant (eg, leukaemic blasts). Platelets: number, size and shape are commented on. Other abnormalities such as parasites, plasma cells and occasionalcirculating carcinoma cells may be found.Preferred Specimen(s)2 slides Peripheral Blood SmearInstructions: 2 glass microscope slide-peripheral smears(preferred)2 smears, unfixed, air-dried accompanied by CBC 9complete blood count0profileinfo

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