Pathology notes

Apr 16th, 2015
Studypool Tutor
Price: $5 USD

Tutor description

Word Count: 969
Showing Page: 1/34
THE PANCREASPrepared by RONO Endocrine-glugagon,somatostatin,insulin Exocrine-produce digestive enzymes ininactive form except amylase andlipase.Stored in zymogen granules. Cuboidal epithelial cells lining the smallerducts secrete bicarbonate rich fluid. Columnar cells in larger ducts-mucin andexpreses the cystic fibrosis conductanceregulator(CTTR) Activation of proenzymes reguires conversionof trypsinogen to trypsin by duodenalenteropeptidase(enterokinase) Trypsin inhibitors-trypsin protein inhibitortype 1(SPINK1) are also secreted by acinar andductal cells. Acinar cells are remarkably resistant to theaction of activated enzymes egtrpsin,chymotrypsin and phospholipase A2.CONGENITAL ANOMALIES1.Agenesis.2.Pacreas divisum.-Failure of the featal duct systems of thepancreatic primordia to fuse.-The relative stenosis caused by the bulk of thepancreatic secresions passing through theminor sphincter predisposes such individualsto chronic pancreatitis.3.Annular pancrease.4.Ectopic pancreas-mostly in stomach andduodenum.5.Congenital cyst-from anomalouse ductdevelopment.PANCREATITIS Infam of the pancrease.ACUTE-can return to normal if the cause ofinflam is removed.CHRONIC-presense of irreversible destruction ofexocrine pancreatic parenchyma.ACUTE PANCREATITIS Severity can range from focal edema and fatnecrosis to widespread parenchymal necrosiswith severe hemorrhage. 80%-due to biliary dse or alco

Review from student

Studypool Student
" <3 it, thanks for saving me time. "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1822 tutors are online

Other Documents


Brown University

1271 Tutors

California Institute of Technology

2131 Tutors

Carnegie Mellon University

982 Tutors

Columbia University

1256 Tutors

Dartmouth University

2113 Tutors

Emory University

2279 Tutors

Harvard University

599 Tutors

Massachusetts Institute of Technology

2319 Tutors

New York University

1645 Tutors

Notre Dam University

1911 Tutors

Oklahoma University

2122 Tutors

Pennsylvania State University

932 Tutors

Princeton University

1211 Tutors

Stanford University

983 Tutors

University of California

1282 Tutors

Oxford University

123 Tutors

Yale University

2325 Tutors