medical notes

Apr 16th, 2015
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EARLY PREGNANCY LOSSDefinitionEarly pregnancy loss: The termination of pregnancy before 20 weeks' gestation or with a fetal weight of <500 g.Spontaneous abortion (SAB): Pregnancy loss before 20 weeks' gestation, as based on last menstrual periodHabitual or recurrent abortion: 3 or more consecutive SABsStillbirth: Pregnancy loss after 20 weeks' gestation (Neonatal loss is the death of a liveborn fetus)Chemical pregnancy loss: Loss of a biochemically evident pregnancyEpidemiologyEarly pregnancy loss is unfortunately the most common complication of human gestation, occurring in at least 75% of all women trying to conceive. Most of these losses are unrecognized and occur before or with the next expected menses. Of those that are recognized, 15-20% are spontaneous abortions (SABs) or ectopic pregnancies diagnosed after the pregnancy is clinically recognized. Approximately 5% of couples trying to conceive have 2 consecutive miscarriages, and approximately 1% of couples have 3 or more consecutive lossesThe incidence of spontaneous miscarriage is 10-15%, whereas the rate of recurrent miscarriage is 3-5%.Most studies demonstrate a spontaneous miscarriage rate of 10-15%. However, the true rate of early pregnancy loss is close to 50% because of the high number of chemical pregnancies that are not recognized in the 2-4 weeks after conception. Most of these pregnancy failures are due to gamete failure (e.g. sperm or oocyte dysfunction).The likelihood for an SAB increas

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