medine and surgery notes

Apr 24th, 2015
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HEREDITARY RENAL DISEASESDr James Swao, RACPPOLYCYSTIC KIDNEY DISEASE(PKD) BOTH RENAL MEDULLA AND CORTEX ARE FILLED WITHCYSTS. INHERITED AS AUTOSOMAL DOMINANT (ADPKD), THECOMMONEST AND (ARPKD WHICH RARE AND DO NOT LIVE LONG) HAS 100% PENETRANCE. CAUSES ENLARGEMENT OF ORGANS INVOLVED ANDAFFECT THEIR FUNCTIONS. AGE GROUP >30 YEARS HIGHEST INCIDENCE AT 45 AND 65 YEARS SOME FAMILIES HAVE HIGH INCIDENCE OFINTRACRANIAL ANEURYSM. HYPERTENSION BEFORE ESRD.CLINICAL PRESENTATION RENAL ANGLE PAIN GROSS HAEMATURIA ABDOMINAL SWELLING OR ENLARGEMENT. HYPERTENSION.CYSTS IN OTHER ORGANS LIVER IN 30% BUT NO HEPATIC SYMPTOMS THOUGH MY HAVE EPIGASTRIC PAIN/DISCOMFORT. SPLEEN, OVARIES, THYROID, PANCREAS ETC.COMPLICATIONS OFADPKD1.PAIN2.ESRD3.HAEMATURIA4.HYPERTENSION5.NEPHROLITHIASIS6.RECURRENT UTI7.STROKEDIAGNOSISHISTORYPALPABLE KIDNEYSHYPERTENSIONASYMPTOMATIC URINARY ABNORMALITIES.IVURENAL ULTRA SOUNDABDOMINAL CT SCANTREATMENT PAIN MANAGEMENT REMOVAL OF RENAL STONES CONTROL HYPERTENSION MANAGE CKD/ESRD TREAT INFECTION. SURGICAL INTERVENTION MAY BE INDICATED IF:A) BLEEDING IS A PROBLEMB) RUPTURE OF THE CYSTENDFUNCTIONAL TUBULAR DISORDER BARTTERS SNDROME:This is a syndrome characterized byhypokalaemia, metabolic alkalosis and normalblood pressure.It is due to the pathology in the ATLH.Mimics loop di

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