Medicine an Surgery notes

Apr 24th, 2015
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SYPHILISDefinition:Syphilis is a complex infectious disease caused by Treponema pallidum, a spirochete capable of infecting almost any organ or tissue in the body and causing protean clinical manifestations Etiology & progression:Transmission occurs most frequently during sexual contact, through minor skin or mucosal lesions; sites of inoculation are usually genital but may be extragenital.The risk of developing syphilis after unprotected sex with an individual with early syphilis is approximately 30-50%. The organism is extremely sensitive to heat and drying but can survive for days in fluids; therefore, it can be transmitted in blood from infected persons. Syphilis can be transferred via the placenta from mother to fetus after the tenth week of pregnancy (congenital syphilis).The natural history of acquired syphilis is generally divided into two major clinical stages: early (infectious) syphilis and late syphilis.The two stages are separated by a symptom-free latent phase during the first part of which (early latency) the infectious stage is liable to recur. Infectious syphilis includes the primary lesions (chancre and regional lymphadenopathy), the secondary lesion

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