Medicine an Surgery notes

Apr 24th, 2015
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MALARIA IN PREGNANCYSince its endemicity determines the level of immunity to it in a community, pregnant women with malaria can be divided into;Immune - native to endemic areasNonimmune/Highly susceptible - with no immunity (Highland malaria - P. falciparum malaria in non-immune people)Malaria in a community may be divided into;Stable - These are areas with constant repeated infections (holoendemic areas) and the population has a high degree of immunity and epidemics have been known to occur e.g. Coast, Nyanza, and parts of EasternUnstable - Regions with intermittent transmission, community immunity is poorly developed and dramatic epidemics, severe attacks of cerebral malaria, black water fever and pulmonary edema can occurInfluence of pregnancy on the course of malariaAcquired immunity to malaria is a temporary phenomenon and is liable to breakdown/decline under conditions of stress e.g. pregnancy, after surgical operations due to withdrawing of protein from the immune system (immunoglobulins) in the face of increased protein requirement with insufficient dietary intake thus the ability to limit parasitemia is reduced so that both parasite rates and densities are higher

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