Medicine an Surgery notes

Apr 25th, 2015
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Peptic ulcer diseasekibaruintroduction Primary peptic ulcer disease is very rare inchildren younger than 10 years, and most casesin this age group are related to secondarycauses. Most children with symptoms of dyspepsia donot have peptic ulcer disease or gastritis. They more likely have nonulcer dyspepsia.Clinical symptoms of peptic disease are poorpredictors of actual pathology. Therefore, upper gastrointestinal endoscopy withmucosal biopsy is the investigation of choice forthe diagnosis of gastritis and peptic ulcerdisease.Minimally invasive tests such as the urea breathtest and stool monoclonal antibody test showpromise as diagnostic tests for Helicobacterpylori in children, although further clinical studiesare necessary to establish their efficacy. Proton pump inhibitors, when compared to othertreatments, including H2 antagonists, are the mosteffective medication in healing peptic ulcerdisease. The term peptic disease includes both gastritisand peptic ulcer disease, closely related entitiesthat exist on a continuous disease spectrum. Gastritis is thought to be a precursor eventleading to ulcer disease. The prevalence of peptic ulcer disease in theadult population is estimated at 5% to 10% but isnot well characterized in children. A study from Toronto estimated that 1 in 2500pediatric hospital admissions was secondary togastric or duodenal ulcers. The incidence of gastri

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