MBchB study guide

Apr 25th, 2015
Studypool Tutor
Price: $5 USD

Tutor description

Word Count: 952
Showing Page: 1/36
GestationalTrophoblasticDiseasesDr Njoroge Waithaka1DefinitionThese are diseases arising fromthe trophoblastic tissue.The trophoblastic tissue consist ofsynciotrophoblast andcytotrophoblast2Types of GTDs1.2.3.4.Hydatidiform MoleInvasive MoleChoriocarcinomaPlacental Site Tumor3IncidenceHydatidiform Mole is thecommonest of these diseases.In Taiwan the incidence is 1:125deliveriesUSA 1:1500 deliveriesKenya 1:370 deliveriesThe incidence of choriocarcinomain Kenya is 1: 8474Associated FactorsMore common at ages below 20yrs andabove 40yrsLow socioeconomic statusLow protein and low folic acid dietsOccur in less than 5%of subsequentpregnancyA blood group A woman with a group Ospouse has a x10 higher riskBlood group AB have a poor prognosis5In choriocarcinoma:50% follow Hmole25% follow abortion25%follow term pregnancy6classificationHydatidiform Mole (True Molar) abnormal pregnancycharacterized by multiple grapelikevesicles filling and distending the uterusin absence of an intactfetus.chromosome are paternal 46xxPartial Mole occurs when the placentahas molar transformation in the 2nd or3rd trimester in presence of a fetus7microscopyThere is edema of the villi stroma,avascular villi,nests of proliferatingsynciotrophoblast andcytotrophoblast elementssurrounding the villi. The likelyhood of malignant transformation

Review from student

Studypool Student
" Outstanding Job!!!! "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1823 tutors are online

Other Documents


Brown University

1271 Tutors

California Institute of Technology

2131 Tutors

Carnegie Mellon University

982 Tutors

Columbia University

1256 Tutors

Dartmouth University

2113 Tutors

Emory University

2279 Tutors

Harvard University

599 Tutors

Massachusetts Institute of Technology

2319 Tutors

New York University

1645 Tutors

Notre Dam University

1911 Tutors

Oklahoma University

2122 Tutors

Pennsylvania State University

932 Tutors

Princeton University

1211 Tutors

Stanford University

983 Tutors

University of California

1282 Tutors

Oxford University

123 Tutors

Yale University

2325 Tutors