Chapter 7 Notes

Jul 8th, 2016
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Lecture Notes generated from the following book: Biology, the Dynamic Science. Russell, Wolfe, Hertz and Starr. 2008. ISBN 978-0-534-24966-3

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Showing Page: 1/53
Cell CommunicationChapter 7Fig. 7-CO, p. 139Cell Communication 75 trillion cells in our bodies Must communicate to survive and reproduce Many other usesmating between single-celled organismsneighboring cells giving out a shouthormone signalingneurotransmitter signalingIntercellular Chemical Messengers Controlling cell Releases signal (ligand) molecule that causesresponse of target cells Target cell processes signal in 3 steps: Reception, transduction, response Signal transduction Series of events from reception to responseVIDEOStages of Cell Signaling Reception signaling molecule (called a ligand) binds to a receptorthat can be found on cell membrane or intracellularlyCell Signaling Signal Transduction signaling molecule changes shape of receptor to initiatetransduction this is similar to translation of a foreign language involves activation of intracellular signal moleculesCell Signaling Response involves just about any cellular activity such as: enzyme activation transcription of DNA cytoskeleton movementSignal TransductionFig. 7-2, p. 1421) Reception by a cell-surface receptorPolar (hydrophilic)signal moleculeActivationReceptorembeddedin plasmamembraneTarget cellPlasmamembranePolar signal molecules cannot pass through theplasma membrane. In this case they bind to a receptoron the surface.Fig. 7-3a, p. 1422) Reception

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