application of financial_research

May 28th, 2015
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RESEARCH & DEVELOPMENT Drug discovery is the process by which potential drugs are discovered or designed. In the past most drugs have been discovered either by isolating the active ingredient from traditional remedies or by serendipitous discovery. Modern biotechnology often focuses on understanding the metabolic pathways related to a disease state or pathogen, and manipulating these pathways usingmolecular biology or biochemistry. A great deal of early-stage drug discovery has traditionally been carried out by universities and research institutions. Public funding accounts for 80% of the amount spent on basic research for new drugs and vaccines in the United States.[4]

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RESEARCH & DEVELOPMENT Drug discoveryis the process by which potentialdrugsare discovered or designed. In the past most drugs have been discovered either by isolating the active ingredient from traditional remedies or byserendipitousdiscovery. Modernbiotechnologyoften focuses on understanding themetabolic pathwaysrelated to adiseasestate orpathogen, and manipulating these pathways usingmolecular biologyorbiochemistry. A great deal of early-stage drug discovery has traditionally been carried out by universities and research institutions.Public fundingaccounts for 80% of the amount spent on basic research for new drugs and vaccines in the United States.[4]Drug developmentrefers to activities undertaken after a compound is identified as a potential drug in order to establish its suitability as a medication. Objectives of drug development are to determine appropriateFormulationandDosing, as well as to establishsafety. Research in these areas generally includes a combination ofin vitrostudies,in vivostudies, andclinical trials. The amount of capital required for late stage development has made it a historical strength of the larger pharmaceutical companies. Suggested citation: Tufts Center for the Study of Drug Development, Annual Impact Report,http://csdd.tufts.edu/[citation needed].The cost of innova

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