Extraction and Degradation Study of Ecdysterone from Leaves of Achyranthes Aspera Linn

Jun 18th, 2015
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Achyranthes aspera Linn. belonging to family Amaranthaceae, is commonly found as a weed on way side and at waste places throughout India.

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Extraction and Degradation Study of Ecdysterone from Leaves of Achyranthes Aspera Linn. (Aghada)Document By: BharadwajVisit my websitewww.Engineeringpapers.blogspot.comMore Papers and Presentations available on above siteAbstract: Batch Extraction of ecdysterone was carried out from leaves of Achyranthes Aspera Linn (Aghada) with methanol as solvent. Soxhlet extraction was carried out to obtain maximum recoverable amount of ecdysterone. Concentration of extracted ecdysterone was measured by RP-HPLC with symmetry C-18 column. During Soxhlet extraction study, degradation of ecdysterone was observed with respect to time and temperature. TGA/DSC analysis of the ecdysterone standard sample was carried out for confirmation of degradation. Keywords: Achyranthes Aspera Linn, Ecdysterone, RP-HPLC, Extraction, Degradation, TGA/DSCIntroductionAchyranthes aspera Linn. belonging to family Amaranthaceae, is commonly found as a weed on way side and at waste places throughout India. It is known as Apamarg in Sanskrit, Aghedo and Aghedi in Gujarati, Chirchira and Chirchitta in Hindi and Prickly chaff flower in English. It is widely used for asthmatic cough, snakebite, hydrophobia, urinary calculi, rabies, influenza, piles, bronchitis, diarrhea, renal dropsy, gonorrhea and abdominal pain [1, 2 & 3]. A powder of dried leaf mixed with honey is useful in the early stages of asthma [4]. One of the drugs from Siddha system of medicine, Naayuruvi kuzhi thailum has A. aspera as the

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