Jun 21st, 2015
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American Sentinel University - Birmingham
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An evidence-based review of medical and surgical treatments of genital wartsNoah Scheinfeld JD MD1, Daniel S Lehman MD2Dermatology Online Journal 12 (3): 51. St Lukes Roosevelt Hospital Center Department of Dermatology, New York NY. NSS32@Columbia.edu2. Maimodides Medical Center Department of UrologyAbstractGenital human papillomavirus (HPV) infection is the most common sexually transmitted disease. Each year 1 million new cases of genital warts are diagnosed, two thirds of which are in women. The estimated prevalence rate in the US population is 15 percent. HPV infects keratinocytes. Such infection can manifest clinically as warts. Treatment options for genital warts are numerous, well established, and effective. Topical treatments include podophyllin resin, imiquimod, trichloroacetic acid, and podophyllotoxin. Surgical or destructive therapies include carbon dioxide laser, surgical excision, loop excision, cryotherapy, and electrodessication. Interferon can be injected locally or administered systemically to treat genital warts. Evidence of efficacy in the treatment of genital warts is drawn from randomized blind-controlled trials, prospective studies, and retrospective cohort studies. Evidence of efficacy appears to be good, but more head-to-head studies and comparisons of combination therapies versus monotherapy need to be done. Treatment of choice depends on the number, size, and location of lesions. There is little certainty that any approach is more effec

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