Case Report of a Very Late-Onset Systemic Lupus Erythematous

Jun 21st, 2015
Studypool Tutor
Central Connecticut State University
Course: general
Price: $25 USD

Tutor description

Late-onset systemic lupus erythematous (SLE) is most often a drug-induced SLE, and is usually a benign form. Use of immunosuppressive drugs is rarely necessary. We report an unusual case of a late-onset, drug-induced neuropsychiatric SLE (NPSLE). Gaelle Leroux, MD, François Piette, MD, and Pascal Chaibi, MD

Word Count: 1592
Showing Page: 1/6
A Case Report of a Very Late-Onset Systemic Lupus ErythematousAuthors:Alice Breining, BS, Anne Sophie Carret-Rebillat, MD, Nathalie Costedoat-Chalumeau, MD, PhD,Gaelle Leroux, MD, Franois Piette, MD, and Pascal Chaibi, MDIntroductionLate-onset systemic lupus erythematous (SLE) is most often a drug-induced SLE, and is usually a benign form. Use of immunosuppressive drugs is rarely necessary. We report an unusual case of a late-onset, drug-induced neuropsychiatric SLE (NPSLE).Case PresentationMrs. R, an 80-year-old Caucasian woman, was hospitalized in 2006 for fever. Her familial history included a sister who had SLE and a daughter who had Basedow disease and multiple sclerosis. Her past medical history included a diagnosis of coronary heart disease in 2003, which justified an angioplasty with the implementation of two stents and treatment with beta blockers, statins, and platelet antiaggregants. In 2004, the patient had an autoimmune hemolysis without anemia but with positive antinuclear antibody (ANA) (titer 1:320), positive anti-DNA antibodies (titer 1:40), low haptoglobin, and highly positive direct Coombs test.For the 6 months prior to her 2006 hospitalization, Mrs. R had been experiencing a progressive loss of autonomy associated with a cognitive dysfunction. She arrived at a geriatric unit for a urinary tract infection with fever. On examination, she was confused and showed an erythematosquamous eruption of the upper chest and cheeks associated with alopec

Review from student

Studypool Student
" Awesome! Exactly what I wanted. "
Ask your homework questions. Receive quality answers!

Type your question here (or upload an image)

1831 tutors are online

Brown University





1271 Tutors

California Institute of Technology




2131 Tutors

Carnegie Mellon University




982 Tutors

Columbia University





1256 Tutors

Dartmouth University





2113 Tutors

Emory University





2279 Tutors

Harvard University





599 Tutors

Massachusetts Institute of Technology



2319 Tutors

New York University





1645 Tutors

Notre Dam University





1911 Tutors

Oklahoma University





2122 Tutors

Pennsylvania State University





932 Tutors

Princeton University





1211 Tutors

Stanford University





983 Tutors

University of California





1282 Tutors

Oxford University





123 Tutors

Yale University





2325 Tutors